Prenatal exposure of mice to the human liver carcinogen aflatoxin B
It has become axiomatic that critical windows of susceptibility to genotoxins exist and that genetic damage in utero may be a trigger for later life cancers. Data supporting this critical window hypothesis are remarkably few. This study provides a quantitative bridge between DNA damage by the liver...
Main Authors: | Thiantanawat, Apinya (Author), Egner, Patricia A. (Author), Groopman, John D. (Author), Chawanthayatham, Supawadee (Contributor), Wogan, Gerald N (Contributor), Croy, Robert G (Contributor), Essigmann, John M (Contributor) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2017-01-26T15:15:53Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Early Detection of the Aflatoxin B₁ Mutational Fingerprint: A Diagnostic Tool for Liver Cancer
by: Fedeles, Bogdan I, et al.
Published: (2018) -
Editor's Highlight: Pregnancy Alters Aflatoxin B1 Metabolism and Increases DNA Damage in Mouse Liver
by: Egner, Patricia A., et al.
Published: (2018) -
Aflatoxin B[subscript 1]-DNA adduct formation and mutagenicity in livers of neonatal female B6C3F1 mice
by: Egner, Patricia A., et al.
Published: (2012) -
Sulforaphane-Mediated Reduction of Aflatoxin B-1-N-7-Guanine in Rat Liver DNA: Impacts of Strain and Sex
by: Fiala, Jeannette Louise Allen, et al.
Published: (2012) -
Mutational spectra of aflatoxin B
by: Fox, Edward J., et al.
Published: (2017)