Designed BH3 Peptides with High Affinity and Specificity for Targeting Mcl-1 in Cells
Mcl-1 is overexpressed in many cancers and can confer resistance to cell-death signaling in refractory disease. Molecules that specifically inhibit Mcl-1 hold potential for diagnosing and disrupting Mcl-1-dependent cell survival. We selected three peptides from a yeast-surface display library that s...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society (ACS),
2017-01-20T20:16:15Z.
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| Subjects: | |
| Online Access: | Get fulltext |