PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal

PPAR-α and glucocorticoid receptor synergize to promote erythroid progenitor self-renewal

Many acute and chronic anaemias, including haemolysis, sepsis and genetic bone marrow failure diseases such as Diamond-Blackfan anaemia, are not treatable with erythropoietin (Epo), because the colony-forming unit erythroid progenitors (CFU-Es) that respond to Epo are either too few in number or are...

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Bibliographic Details
Main Authors: Lee, Hsiang-Ying (Author), Gao, Xiaofei (Author), Barrasa, M. Inmaculada (Author), Li, Hu (Author), Elmes, Russell R. (Author), Peters, Luanne L. (Author), Lodish, Harvey F (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-12-02T18:52:49Z.
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