2D-Visualisierung des zellulären Sauerstoff verbrauchs in Mikrofluidiksystemen

2D-Visualisierung des zellulären Sauerstoff verbrauchs in Mikrofluidiksystemen

A new imaging system allows visualizing oxygen distributions in 2D. Combining sensor foils with microfluidic devices enables online monitoring of cellular oxygen consumption in whole chip areas. Furthermore, suitable device materials depending on application and cell line can be determined. Numerica...

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Bibliographic Details
Main Authors: Kasuya, Junichi (Contributor), Pavesi, Andrea (Author), Liebsch, Gregor (Author), Ochs, Christopher J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Mechanobiology Lab (Contributor)
Format: Article
Language:English
Published: Springer Berlin Heidelberg, 2016-08-25T18:41:33Z.
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Summary:A new imaging system allows visualizing oxygen distributions in 2D. Combining sensor foils with microfluidic devices enables online monitoring of cellular oxygen consumption in whole chip areas. Furthermore, suitable device materials depending on application and cell line can be determined. Numerically simulated oxygen consumption of rat lung microvascular endothelial cells and rat hepatocytes was experimentally validated.

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