Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Eukaryotic cells compartmentalize biochemical processes in different organelles, often relying on metabolic cycles to shuttle reducing equivalents across intracellular membranes. NADPH serves as the electron carrier for the maintenance of redox homeostasis and reductive biosynthesis, with separate c...

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Main Authors: Lewis, Caroline A (Author), Parker, Seth J (Author), Fiske, Brian Prescott (Contributor), McCloskey, Douglas (Author), Gui, Dan Yi (Contributor), Green, Courtney R. (Author), Feist, Adam M. (Author), Vander Heiden, Matthew G. (Contributor), Metallo, Christian M. (Author), Vokes, Natalie I. (Author), Lewis, Caroline (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Lewis, Caroline A. (Contributor), Vokes, Natalie (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-08-15T17:24:40Z.
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