Subtle balance of tropoelastin molecular shape and flexibility regulates dynamics and hierarchical assembly
The assembly of the tropoelastin monomer into elastin is vital for conferring elasticity on blood vessels, skin, and lungs. Tropoelastin has dual needs for flexibility and structure in self-assembly. We explore the structure-dynamics-function interplay, consider the duality of molecular order and di...
Main Authors: | Yeo, Giselle C. (Author), Tarakanova, Anna (Contributor), Baldock, Clair (Author), Wise, Steven G. (Author), Weiss, Anthony S. (Author), Buehler, Markus J (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor), Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics (Contributor), Buehler, Markus J. (Contributor) |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2016-03-17T12:14:19Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Tropoelastin is a Flexible Molecule that Retains its Canonical Shape
by: Tarakanova, Anna, et al.
Published: (2020) -
Molecular model of human tropoelastin and implications of associated mutations
by: Yeo, Giselle C., et al.
Published: (2019) -
Tropoelastin and Elastin Assembly
by: Jazmin Ozsvar, et al.
Published: (2021-02-01) -
Molecular structure, hierarchical assembly and stimuli-responsive mechanics of tropoelastin and elastin biomaterials
by: Tarakanova, Anna
Published: (2017) -
Coarse-grained model of tropoelastin self-assembly into nascent fibrils
by: A. Tarakanova, et al.
Published: (2019-06-01)