Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
The mammalian target of rapamycin complex 1 (mTORC1) is the key signaling hub that regulates cellular protein homeostasis, growth, and proliferation in health and disease. As a prerequisite for activation of mTORC1 by hormones and mitogens, there first has to be an available pool of intracellular am...
| Main Authors: | , , , , , , , , , , , , |
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| Other Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications, Ltd.,
2016-03-03T00:47:54Z.
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| Subjects: | |
| Online Access: | Get fulltext |