Oscillatory three-phase flow reactor for studies of bi-phasic catalytic reactions

A multi-phase flow strategy, based on oscillatory motion of a bi-phasic slug within a fluorinated ethylene propylene (FEP) tubular reactor, under inert atmosphere, is designed and developed to address mixing and mass transfer limitations associated with continuous slug flow chemistry platforms for s...

Full description

Bibliographic Details
Main Authors: Abolhasani, Milad (Contributor), Bruno, Nicholas C. (Contributor), Jensen, Klavs F. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: Royal Society of Chemistry, 2016-02-17T16:21:32Z.
Subjects:
Online Access:Get fulltext
Description
Summary:A multi-phase flow strategy, based on oscillatory motion of a bi-phasic slug within a fluorinated ethylene propylene (FEP) tubular reactor, under inert atmosphere, is designed and developed to address mixing and mass transfer limitations associated with continuous slug flow chemistry platforms for studies of bi-phasic catalytic reactions. The technique is exemplified with C-C and C-N Pd catalyzed coupling reactions.
Novartis-MIT Center for Continuous Manufacturing