Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8

Kinesin-8s are plus-end-directed motors that negatively regulate microtubule (MT) length. Well-characterized members of this subfamily (Kip3, Kif18A) exhibit two important properties: (i) They are "ultraprocessive," a feature enabled by a second MT-binding site that tethers the motors to a...

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Bibliographic Details
Main Authors: Shin, Yongdae (Contributor), Du, Yaqing (Author), Collier, Scott E. (Author), Ohi, Melanie D. (Author), Lang, Matthew J. (Author), Ohi, Ryoma (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2016-02-05T02:01:18Z.
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