Biased Brownian motion as a mechanism to facilitate nanometer-scale exploration of the microtubule plus end by a kinesin-8
Kinesin-8s are plus-end-directed motors that negatively regulate microtubule (MT) length. Well-characterized members of this subfamily (Kip3, Kif18A) exhibit two important properties: (i) They are "ultraprocessive," a feature enabled by a second MT-binding site that tethers the motors to a...
Main Authors: | Shin, Yongdae (Contributor), Du, Yaqing (Author), Collier, Scott E. (Author), Ohi, Melanie D. (Author), Lang, Matthew J. (Author), Ohi, Ryoma (Author) |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
National Academy of Sciences (U.S.),
2016-02-05T02:01:18Z.
|
Subjects: | |
Online Access: | Get fulltext |
Similar Items
-
Reconstitution of dynein transport to the microtubule plus end by kinesin
by: Anthony J Roberts, et al.
Published: (2014-06-01) -
Electrostatically biased binding of kinesin to microtubules.
by: Barry J Grant, et al.
Published: (2011-11-01) -
Structure-based molecular simulations reveal the enhancement of biased Brownian motions in single-headed kinesin.
by: Ryo Kanada, et al.
Published: (2013-01-01) -
Ahead of the Curve: New Insights into Microtubule Dynamics [version 1; referees: 2 approved]
by: Ryoma Ohi, et al.
Published: (2016-03-01) -
Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters
by: Stephen R. Norris, et al.
Published: (2018-07-01)