The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis

Background The tumor microenvironment has complex effects in cancer pathophysiology that are not fully understood. Most cancer therapies are directed against malignant cells specifically, leaving pro-malignant signals from the microenvironment unaddressed. Defining specific mechanisms by which the t...

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Bibliographic Details
Main Authors: Xu, Kun (Author), Tian, Xuejun (Author), Movassaghi, Mohammad (Contributor), Kuperwasser, Charlotte (Author), Oh, Sun Y. (Author), Naber, Stephen P. (Author), Buchsbaum, Rachel J. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: BioMed Central, 2016-02-03T17:16:31Z.
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