The fibroblast Tiam1-osteopontin pathway modulates breast cancer invasion and metastasis
Background The tumor microenvironment has complex effects in cancer pathophysiology that are not fully understood. Most cancer therapies are directed against malignant cells specifically, leaving pro-malignant signals from the microenvironment unaddressed. Defining specific mechanisms by which the t...
Main Authors: | Xu, Kun (Author), Tian, Xuejun (Author), Movassaghi, Mohammad (Contributor), Kuperwasser, Charlotte (Author), Oh, Sun Y. (Author), Naber, Stephen P. (Author), Buchsbaum, Rachel J. (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry (Contributor) |
Format: | Article |
Language: | English |
Published: |
BioMed Central,
2016-02-03T17:16:31Z.
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Subjects: | |
Online Access: | Get fulltext |
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