Molecular dynamic simulation studies of three novel Gerstmann - Straussler - Scheinker and Creutzfeldt - Jacob Prion mutations
The transformation of normal prion protein into pathogenic variant in transmissible spongiform encephalopathy (TSE) is expedited by mutations. Three novel mutations V176G, E196A and I215V are associated with Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker syndrome (GSS). These mu...
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| Format: | Thesis |
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2016-02.
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| Online Access: | Get fulltext |