The mechanism of action of the negative Regulators of jak/stat singnaling pathway in Resistant FLT-ITD acute myeloid leukaemia cells
The aim of this study was to understand the mechanism of action of negative regulators of JAK/STAT signalling pathway in FLT3-ITD AML cell lines with different response towards the FLT3 inhibitors PKC412 and CEP701. The cytotoxic dose of CEP-701 and PKC-412 on resistant cell lines was significantly...
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| Format: | Article |
| Language: | English |
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Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia,
2019.
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| Online Access: | Get fulltext |