Modelling the effect of genes on the dynamics of probabilistic spiking neural networks for computational neurogenetic modelling

Computational neuro-genetic models (CNGM) combine two dynamic models - a gene regulatory network (GRN) model at a lower level, and a spiking neural network (SNN) model at a higher level to model the dynamic interaction between genes and spiking patterns of activity under certain conditions. The pape...

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Bibliographic Details
Main Authors: Kasabov, N (Author), Schliebs, S (Author), Mohemmed, A (Author)
Format: Others
Published: AUT University, 2011-08-09T03:15:24Z.
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Online Access:Get fulltext
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001 1663
042 |a dc 
100 1 0 |a Kasabov, N  |e author 
700 1 0 |a Schliebs, S  |e author 
700 1 0 |a Mohemmed, A  |e author 
245 0 0 |a Modelling the effect of genes on the dynamics of probabilistic spiking neural networks for computational neurogenetic modelling 
260 |b AUT University,   |c 2011-08-09T03:15:24Z. 
500 |a 8th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, Gargnano-Lago di Garda, Italy, 2011-06-30 - 2011-07-02 
520 |a Computational neuro-genetic models (CNGM) combine two dynamic models - a gene regulatory network (GRN) model at a lower level, and a spiking neural network (SNN) model at a higher level to model the dynamic interaction between genes and spiking patterns of activity under certain conditions. The paper demonstrates that it is possible to model and trace over time the effect of a gene on the total spiking behavior of the SNN when the gene controls a parameter of a stochastic spiking neuron model used to build the SNN. Such CNGM can be potentially used to study neurodegenerative diseases or develop CNGM for cognitive robotics. 1 
540 |a OpenAccess 
650 0 4 |a Computational neurogenetic modeling 
650 0 4 |a Spiking neural networks 
650 0 4 |a Gene regulatory networks 
650 0 4 |a Probabilistic neural models 
655 7 |a Conference Contribution 
856 |z Get fulltext  |u http://hdl.handle.net/10292/1663