Bias in animal studies of estrogen effects on cardiovascular disease: A systematic review and meta‐analysis

Bias in animal studies of estrogen effects on cardiovascular disease: A systematic review and meta‐analysis

Abstract Background Randomized controlled trials on menopausal hormone therapy in humans have not confirmed the benefit of estrogens on cardiovascular disease found in animal studies. Flawed methodology or publication bias in animal studies may explain the dicrepancy. Objectives The aim of this stud...

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Bibliographic Details
Main Authors: Christopher Friis Berntsen, Pernille Rootwelt, Anders Erik Astrup Dahm
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
animals
cardiovascular disease
estrogens
publication bias
systematic review
Online Access:https://doi.org/10.1002/rth2.12507

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