Development of Sustained-Release Ophthalmic Formulation Based on Tranilast Solid Nanoparticles

Development of Sustained-Release Ophthalmic Formulation Based on Tranilast Solid Nanoparticles

Eye drops containing Tranilast (TL), N-(3,4-dimethoxycinnamoyl) anthramilic acid, are used as an anti-allergic conjunctivitis drug in the ophthalmic field. Traditional eye drops are very patient compliant, although the bioavailability (<i>BA</i>) of most eye drops is low since eye drops...

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Bibliographic Details
Main Authors: Misa Minami, Ryotaro Seiriki, Hiroko Otake, Yosuke Nakazawa, Kazutaka Kanai, Tadatoshi Tanino, Noriaki Nagai
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Materials
Subjects:
tranilast
sustained delivery system
lacrimal fluid
eyelid
meibomian glands
Online Access:https://www.mdpi.com/1996-1944/13/7/1675

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