Designed and biologically active protein lattices

Designed and biologically active protein lattices

Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retenti...

Full description

Bibliographic Details
Main Authors: Shih-Ting Wang, Brian Minevich, Jianfang Liu, Honghu Zhang, Dmytro Nykypanchuk, James Byrnes, Wu Liu, Lev Bershadsky, Qun Liu, Tong Wang, Gang Ren, Oleg Gang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23966-4
id doaj-fff27e4143024037b51fe7d8436773cc
record_format Article
spelling doaj-fff27e4143024037b51fe7d8436773cc2021-06-20T11:12:29ZengNature Publishing GroupNature Communications2041-17232021-06-0112111110.1038/s41467-021-23966-4Designed and biologically active protein latticesShih-Ting Wang0Brian Minevich1Jianfang Liu2Honghu Zhang3Dmytro Nykypanchuk4James Byrnes5Wu Liu6Lev Bershadsky7Qun Liu8Tong Wang9Gang Ren10Oleg Gang11Center for Functional Nanomaterials, Brookhaven National LaboratoryDepartment of Chemical Engineering, Columbia UniversityThe Molecular Foundry, Lawrence Berkeley National LaboratoryCenter for Functional Nanomaterials, Brookhaven National LaboratoryCenter for Functional Nanomaterials, Brookhaven National LaboratoryEnergy Sciences Directorate/Photon Science Division, NSLS II, Brookhaven National LaboratoryBiology Department, Brookhaven National LaboratoryCenter for Functional Nanomaterials, Brookhaven National LaboratoryBiology Department, Brookhaven National LaboratoryAdvanced Science Research Center at the Graduate Center of the City University of New YorkThe Molecular Foundry, Lawrence Berkeley National LaboratoryCenter for Functional Nanomaterials, Brookhaven National LaboratoryOrganising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.https://doi.org/10.1038/s41467-021-23966-4
collection DOAJ
language English
format Article
sources DOAJ
author Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
spellingShingle Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
Designed and biologically active protein lattices
Nature Communications
author_facet Shih-Ting Wang
Brian Minevich
Jianfang Liu
Honghu Zhang
Dmytro Nykypanchuk
James Byrnes
Wu Liu
Lev Bershadsky
Qun Liu
Tong Wang
Gang Ren
Oleg Gang
author_sort Shih-Ting Wang
title Designed and biologically active protein lattices
title_short Designed and biologically active protein lattices
title_full Designed and biologically active protein lattices
title_fullStr Designed and biologically active protein lattices
title_full_unstemmed Designed and biologically active protein lattices
title_sort designed and biologically active protein lattices
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-06-01
description Organising proteins in 2D and 3D is needed to develop complex bimolecular materials for a range of applications. Here, the authors report the encapsulation of ferritin and apoferritin in DNA-based voxels with programmed assembly to generate both 2D and 3D protein lattices and demonstrate the retention of protein function.
url https://doi.org/10.1038/s41467-021-23966-4
work_keys_str_mv AT shihtingwang designedandbiologicallyactiveproteinlattices
AT brianminevich designedandbiologicallyactiveproteinlattices
AT jianfangliu designedandbiologicallyactiveproteinlattices
AT honghuzhang designedandbiologicallyactiveproteinlattices
AT dmytronykypanchuk designedandbiologicallyactiveproteinlattices
AT jamesbyrnes designedandbiologicallyactiveproteinlattices
AT wuliu designedandbiologicallyactiveproteinlattices
AT levbershadsky designedandbiologicallyactiveproteinlattices
AT qunliu designedandbiologicallyactiveproteinlattices
AT tongwang designedandbiologicallyactiveproteinlattices
AT gangren designedandbiologicallyactiveproteinlattices
AT oleggang designedandbiologicallyactiveproteinlattices
_version_ 1721370406216007680

Similar Items