Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children.

Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children.

HIV causes defects in memory B cells in children, but the mechanisms of those defects have not been fully elucidated. One possible mechanism is the lack of T-cell help to B cells during immune reactions. However, few studies have assessed the effect of HIV on follicular helper T cells (TFH cells) in...

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Bibliographic Details
Main Authors: Daniel M Muema, Gladys N Macharia, Babatunde A Olusola, Amin S Hassan, Greg W Fegan, James A Berkley, Britta C Urban, Eunice W Nduati
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5405965?pdf=render

Internet

http://europepmc.org/articles/PMC5405965?pdf=render

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