Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

Safety and immunogenicity of an attenuated Chinese pseudorabies variant by dual deletion of TK&gE genes

Abstract Background Since the outbreak of a new emerging virulent pseudorabies virus mutant in Chinese pig herds, intensive research has been focused on the construction of novel gene deletion vaccine based on the variant virulent viruses. An ideal vaccine candidate is expected to have a balanced sa...

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Bibliographic Details
Main Authors: Jichun Wang, Zengcai Song, Aimin Ge, Rongli Guo, Yongfeng Qiao, Mengwei Xu, Zhisheng Wang, Yamei Liu, Yating Zheng, Hongjie Fan, Jibo Hou
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Veterinary Research
Subjects:
Pseudorabies virus emerging variant
TK&gE dual deletion
Attenuation
Live vaccine
Safety
Immunogenicity
Online Access:http://link.springer.com/article/10.1186/s12917-018-1536-7

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