Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation

Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation

Identification of targetable molecular changes is essential for selecting appropriate treatment in patients with advanced lung adenocarcinoma. <i>Methods</i>: In this study, a Sanger sequencing plus Fluorescence In Situ Hybridization (FISH) sequential approach was compared with a Next-Ge...

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Bibliographic Details
Main Authors: Maria Gabriela O. Fernandes, Maria Jacob, Natália Martins, Conceição Souto Moura, Susana Guimarães, Joana Pereira Reis, Ana Justino, Maria João Pina, Luís Cirnes, Catarina Sousa, Josué Pinto, José Agostinho Marques, José Carlos Machado, Venceslau Hespanhol, José Luis Costa
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
lung cancer
targeted therapy
next-generation sequencing
molecular profiling
Online Access:https://www.mdpi.com/2072-6694/11/9/1229

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