ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages

<p>Abstract</p> <p>Background</p> <p>We have previously reported that ATP treatment of <it>M bovis</it>-BCG infected human macrophages induces P2X<sub>7 </sub>receptor-dependent killing of intracellular mycobacteria. The mechanism mediating this...

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Bibliographic Details
Main Authors: Croudace Joanne E, Lee Wing-Yiu, Qureshi Omar S, Biswas Debasis, Mura Manuela, Lammas David A
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/9/35