Activity of CK2α protein kinase is required for efficient replication of some HPV types.

Inhibition of human papillomavirus (HPV) replication is a promising therapeutic approach for intervening with HPV-related pathologies. Primary targets for interference are two viral proteins, E1 and E2, which are required for HPV replication. Both E1 and E2 are phosphoproteins; thus, the protein kin...

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Bibliographic Details
Main Authors: Alla Piirsoo, Marko Piirsoo, Martin Kala, Eve Sankovski, Elina Lototskaja, Viktor Levin, Mauro Salvi, Mart Ustav
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007788