Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation

Streptococcus pneumoniae Endopeptidase O Promotes the Clearance of Staphylococcus aureus and Streptococcus pneumoniae via SH2 Domain-Containing Inositol Phosphatase 1-Mediated Complement Receptor 3 Upregulation

Increasing evidences demonstrate that microorganism and their products protect against bacterial and viral pathogens through various mechanisms including immunomodulation. Streptococcus pneumoniae endopeptidase O (PepO), a pneumococcal virulence protein, has been proven to enhance the phagocytosis o...

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Bibliographic Details
Main Authors: Sijie Li, Hong Zhang, Jiangming Xiao, Taixian Yuan, Zhaoche Shu, Yajun Min, Wenchun Xu, Yibing Yin, Xuemei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
PepO
SHIP1
CR3
S. aureus
S. pneumoniae
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00358/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2020.00358/full

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