Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scrambling.

Considerable evidence now supports the idea that the moderate telomere lengthening produced by recombinational telomere elongation (RTE) in a Kluyveromyces lactis telomerase deletion mutant occurs through a roll-and-spread mechanism. However, it is unclear whether this mechanism can account for othe...

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Bibliographic Details
Main Authors: Jianing Xu, Michael J McEachern
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3486848?pdf=render