Regulatory Roles of Drosophila Insulin-Like Peptide 1 (DILP1) in Metabolism Differ in Pupal and Adult Stages

The insulin/IGF-signaling pathway is central in control of nutrient-dependent growth during development, and in adult physiology and longevity. Eight insulin-like peptides (DILP1–8) have been identified in Drosophila, and several of these are known to regulate growth, metabolism, reproduction, stres...

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Bibliographic Details
Main Authors: Sifang Liao, Stephanie Post, Philipp Lehmann, Jan A. Veenstra, Marc Tatar, Dick R. Nässel
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/article/10.3389/fendo.2020.00180/full