RNA-Binding Proteins in the Control of LPS-Induced Macrophage Response

RNA-Binding Proteins in the Control of LPS-Induced Macrophage Response

Innate immune response is triggered by pathogen components, like lipopolysaccharides (LPS) of gram-negative bacteria. LPS initiates Toll-like receptor 4 (TLR4) signaling, which involves mitogen activated protein kinases (MAPK) and nuclear factor kappa B (NFκB) in different pathway branches and ultim...

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Bibliographic Details
Main Authors: Dirk H. Ostareck, Antje Ostareck-Lederer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Genetics
Subjects:
RNA-binding proteins
post-transcriptional regulation
inflammation
bacterial lipopolysaccharides
macrophage activation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00031/full

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