Dendrimeric Poly(Epsilon-Lysine) Delivery Systems for the Enhanced Permeability of Flurbiprofen across the Blood-Brain Barrier in Alzheimer’s Disease

Dendrimeric Poly(Epsilon-Lysine) Delivery Systems for the Enhanced Permeability of Flurbiprofen across the Blood-Brain Barrier in Alzheimer’s Disease

Alzheimer’s disease (AD) is a progressive brain disorder and age-related disease characterised by abnormal accumulation of β-amyloid (Aβ). The development of drugs to combat AD is hampered by the lack of therapeutically-active molecules able to cross the blood-brain barri...

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Bibliographic Details
Main Authors: Shafq Al-azzawi, Dhafir Masheta, Anna L. Guildford, Gary Phillips, Matteo Santin
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
blood-brain barrier
dendrimers
drug delivery system
neurodegenerative disease
Online Access:http://www.mdpi.com/1422-0067/19/10/3224

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