Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer

Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity. Cytokine receptors transduce important signals that regulate proliferation, survival, activation status, and trigger effector functions. Here, we review the roles of major...

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Bibliographic Details
Main Authors: Rizwan Romee, Jeffrey W. Leong, Todd A. Fehniger
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Scientifica
Online Access:http://dx.doi.org/10.1155/2014/205796