Levels of ADAM10 are reduced in Alzheimer’s disease CSF
Abstract Background The disintegrin metalloproteinase 10 (ADAM10) is the main α-secretase acting in the non-amyloidogenic processing of the amyloid precursor protein. This study assesses whether ADAM10 is present in cerebrospinal fluid (CSF), and whether it has potential as a biomarker for Alzheimer...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-07-01
|
| Series: | Journal of Neuroinflammation |
| Online Access: | http://link.springer.com/article/10.1186/s12974-018-1255-9 |