A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

Although the CA2 region of the hippocampus has been implicated in social memory, its precise role has been unclear. Here, the authors show that the dorsal subregion of CA2 is required for the encoding, consolidation and recall of social memory through a circuit linking it to ventral CA1.

Bibliographic Details
Main Authors:	Torcato Meira, Felix Leroy, Eric W. Buss, Azahara Oliva, Jung Park, Steven A. Siegelbaum
Format:	Article
Language:	English
Published:	Nature Publishing Group 2018-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-018-06501-w

id	doaj-ff837dcf6e994d46a57ff2fc9ec8bcbc
record_format	Article
spelling	doaj-ff837dcf6e994d46a57ff2fc9ec8bcbc2021-05-11T09:44:32ZengNature Publishing GroupNature Communications2041-17232018-10-019111410.1038/s41467-018-06501-wA hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamicsTorcato Meira0Felix Leroy1Eric W. Buss2Azahara Oliva3Jung Park4Steven A. Siegelbaum5Department of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityDepartment of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityDepartment of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityDepartment of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityDepartment of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityDepartment of Neuroscience, Zuckerman and Kavli Institutes, Vagelos College of Physicians and Surgeons, Columbia UniversityAlthough the CA2 region of the hippocampus has been implicated in social memory, its precise role has been unclear. Here, the authors show that the dorsal subregion of CA2 is required for the encoding, consolidation and recall of social memory through a circuit linking it to ventral CA1.https://doi.org/10.1038/s41467-018-06501-w
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Torcato Meira Felix Leroy Eric W. Buss Azahara Oliva Jung Park Steven A. Siegelbaum
spellingShingle	Torcato Meira Felix Leroy Eric W. Buss Azahara Oliva Jung Park Steven A. Siegelbaum A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics Nature Communications
author_facet	Torcato Meira Felix Leroy Eric W. Buss Azahara Oliva Jung Park Steven A. Siegelbaum
author_sort	Torcato Meira
title	A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
title_short	A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
title_full	A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
title_fullStr	A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
title_full_unstemmed	A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
title_sort	hippocampal circuit linking dorsal ca2 to ventral ca1 critical for social memory dynamics
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2018-10-01
description	Although the CA2 region of the hippocampus has been implicated in social memory, its precise role has been unclear. Here, the authors show that the dorsal subregion of CA2 is required for the encoding, consolidation and recall of social memory through a circuit linking it to ventral CA1.
url	https://doi.org/10.1038/s41467-018-06501-w
work_keys_str_mv	AT torcatomeira ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT felixleroy ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT ericwbuss ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT azaharaoliva ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT jungpark ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT stevenasiegelbaum ahippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT torcatomeira hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT felixleroy hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT ericwbuss hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT azaharaoliva hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT jungpark hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics AT stevenasiegelbaum hippocampalcircuitlinkingdorsalca2toventralca1criticalforsocialmemorydynamics
_version_	1721449360756047872

A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics

Similar Items