Combination of Silibinin and Curcumin Reduced Leptin Receptor Expression in MCF-7 Human Breast Cancer Cell Line

Background: Leptin and leptin receptor (Ob-R) are associated with worse prognosis, distant metastasis, and poor survival of breast cancer. We investigated the cytotoxic effect of silibinin and curcumin, individually and combined, on Ob-R expression in MCF-7 cells.<br />Methods: This study was...

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Bibliographic Details
Main Authors: Somaye Dalimi-Asl, Hossein Babaahmadi-Rezaei, Ghorban Mohammadzadeh
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2020-11-01
Series:Iranian Journal of Medical Sciences
Subjects:
Online Access:https://ijms.sums.ac.ir/article_46840_49e8cffd817b36842ee7096ee56a1d46.pdf