Clinical Significance of Serum Soluble TNF Receptor I/II Ratio for the Differential Diagnosis of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome From Other Autoinflammatory Diseases

Clinical Significance of Serum Soluble TNF Receptor I/II Ratio for the Differential Diagnosis of Tumor Necrosis Factor Receptor-Associated Periodic Syndrome From Other Autoinflammatory Diseases

Objectives: Genetic analysis of TNFRSF1A can confirm the diagnosis of tumor necrosis factor receptor-associated periodic syndrome (TRAPS), but interpretation of the pathogenesis of variants of unknown significance is sometimes required. The aim of this study was to evaluate the clinical significance...

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Bibliographic Details
Main Authors: Junko Yasumura, Masaki Shimizu, Tomoko Toma, Masato Yashiro, Akihiro Yachie, Satoshi Okada
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
familial Mediterranean fever
Kawasaki disease (KD)
soluble tumor necrosis factor receptor
systemic juvenile idiopathic arthritis (sJIA)
tumor necrosis factor receptor associated periodic syndrome (TRAPS)
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.576152/full

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