Disruption of Transverse-Tubules Eliminates the Slow Force Response to Stretch in Isolated Rat Trabeculae

Disruption of Transverse-Tubules Eliminates the Slow Force Response to Stretch in Isolated Rat Trabeculae

Ventricular muscle has a biphasic response to stretch. There is an immediate increase in force that coincides with the stretch which is followed by a second phase that takes several minutes for force to develop to a new steady state. The initial increase in force is due to changes in myofilament pro...

Full description

Bibliographic Details
Main Authors: Amelia Power, Sarbjot Kaur, Cameron Dyer, Marie-Louise Ward
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Physiology
Subjects:
slow force response
t-tubules
ventricular trabeculae
calcium
β-adrenergic activation
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00193/full

Similar Items

Similar Items