Association of the common genetic polymorphisms and haplotypes of the chymase gene with left ventricular mass in male patients with symptomatic aortic stenosis.

Association of the common genetic polymorphisms and haplotypes of the chymase gene with left ventricular mass in male patients with symptomatic aortic stenosis.

We investigated the association between polymorphisms and haplotypes of the chymase 1 gene (CMA1) and the left ventricular mass index (LVM/BSA) in a large cohort of patients with aortic stenosis (AS). Additionally, the gender differences in cardiac remodeling and hypertrophy were analyzed. The genet...

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Bibliographic Details
Main Authors: Ewa Orlowska-Baranowska, Jaroslaw Gora, Rafal Baranowski, Patrycjusz Stoklosa, Lucja Gadomska vel Betka, Ewa Pedzich-Placha, Malogrzata Milkowska, Marta K Koblowska, Tomasz Hryniewiecki, Zbigniew Gaciong, Grzegorz Placha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4019480?pdf=render

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