Effect of hypoxia and Beraprost sodium on human pulmonary arterial smooth muscle cell proliferation: the role of p27<sup>kip1</sup>

<p>Abstract</p> <p>Background</p> <p>Hypoxia induces the proliferation of pulmonary arterial smooth muscle cell (PASMC) <it>in vivo </it>and <it>in vitro</it>, and prostacyclin analogues are thought to inhibit the growth of PASMC. Previous studie...

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Bibliographic Details
Main Authors: Miyamori Isamu, Ameshima Shingo, Demura Yoshiki, Mizuno Shiro, Kadowaki Maiko, Ishizaki Takeshi
Format: Article
Language:English
Published: BMC 2007-11-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/8/1/77