MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma

MicroRNA-10b regulates epithelial–mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma

Abstract Background Our previous work showed that miR-10b was overexpressed in hepatocellular carcinoma (HCC) and promoted HCC cell migration and invasion. Epithelial–mesenchymal transition (EMT) is involved in HCC metastasis. So, we suspected that miR-10b might participate in the HCC EMT. Methods W...

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Bibliographic Details
Main Authors: Gulibaha Hujie, Sheng-hua Zhou, Hua Zhang, Jie Qu, Xiao-wei Xiong, Outikuer Hujie, Cheng-gong Liao, Shun-e Yang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Cancer Cell International
Subjects:
miR-10b
Hepatocellular carcinoma
Epithelial–mesenchymal transition
KLF4
KLF11
Online Access:http://link.springer.com/article/10.1186/s12935-018-0508-0

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