Use of the kojA promoter, involved in kojic acid biosynthesis, for polyketide production in Aspergillus oryzae: implications for long-term production

Use of the kojA promoter, involved in kojic acid biosynthesis, for polyketide production in Aspergillus oryzae: implications for long-term production

Abstract Background Aspergillus oryzae, a useful industrial filamentous fungus, produces limited varieties of secondary metabolites, such as kojic acid. Thus, for the production of valuable secondary metabolites by genetic engineering, the species is considered a clean host, enabling easy purificati...

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Bibliographic Details
Main Authors: Koichi Tamano, Mahoko Kuninaga, Naoshi Kojima, Myco Umemura, Masayuki Machida, Hideaki Koike
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Biotechnology
Subjects:
Aspergillus oryzae
Kojic acid
Secondary metabolism
Transcriptional regulation
Polyketide
Online Access:http://link.springer.com/article/10.1186/s12896-019-0567-x

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http://link.springer.com/article/10.1186/s12896-019-0567-x

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