Key Macrophage Responses to Infection With Mycobacterium tuberculosis Are Co-Regulated by microRNAs and DNA Methylation

Key Macrophage Responses to Infection With Mycobacterium tuberculosis Are Co-Regulated by microRNAs and DNA Methylation

Tuberculosis (TB) is the leading cause of death from infection with a single bacterial pathogen. Host macrophages are the primary cell type infected with Mycobacterium tuberculosis (Mtb), the organism that causes TB. Macrophage response pathways are regulated by various factors, including microRNAs...

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Bibliographic Details
Main Authors: Monika Looney, Rachel Lorenc, Marc K. Halushka, Petros C. Karakousis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
macrophages
microRNAs
methylation
host response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.685237/full

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