Trauma-induced regulation of VHP-1 modulates the cellular response to mechanical stress

The nervous system utilizes adaptive strategies to mitigate trauma-induced neurodegeneration. Here, the authors report that a MAPK phosphatase VHP-1 is induced by trauma and regulates transcriptional responses to mechanical stress in a C. elegans model.

Bibliographic Details
Main Authors: Nathan Egge, Sonja L. B. Arneaud, Rene Solano Fonseca, Kielen R. Zuurbier, Jacob McClendon, Peter M. Douglas
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21611-8
Description
Summary:The nervous system utilizes adaptive strategies to mitigate trauma-induced neurodegeneration. Here, the authors report that a MAPK phosphatase VHP-1 is induced by trauma and regulates transcriptional responses to mechanical stress in a C. elegans model.
ISSN:2041-1723