Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid

The pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an oxidoreductase from the megaplasmid was addressed. The experimental and modeling data...

Full description

Bibliographic Details
Main Authors: Marius Mihasan, Vlad Artenie
Format: Article
Language:English
Published: "Alexandru Ioan Cuza" University of Iași 2008-08-01
Series:Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
Online Access:http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/708
id doaj-ff3279b96e194c18b676be2fb248e8d7
record_format Article
spelling doaj-ff3279b96e194c18b676be2fb248e8d72020-11-25T02:30:06Zeng"Alexandru Ioan Cuza" University of IașiAnalele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara 1582-35712248-32762008-08-0193701Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmidMarius MihasanVlad ArtenieThe pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an oxidoreductase from the megaplasmid was addressed. The experimental and modeling data showed that the enzyme is tetrameric, has an ligand binding place close to the EKP conserved sequence and might prefer as substrate ketohexoses.http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/708
collection DOAJ
language English
format Article
sources DOAJ
author Marius Mihasan
Vlad Artenie
spellingShingle Marius Mihasan
Vlad Artenie
Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
author_facet Marius Mihasan
Vlad Artenie
author_sort Marius Mihasan
title Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
title_short Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
title_full Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
title_fullStr Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
title_full_unstemmed Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
title_sort computer-based modeling for sugar preferences of an oxidoreducatse from arthrobacter nicotinovorans pao1 plasmid
publisher "Alexandru Ioan Cuza" University of Iași
series Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara
issn 1582-3571
2248-3276
publishDate 2008-08-01
description The pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an oxidoreductase from the megaplasmid was addressed. The experimental and modeling data showed that the enzyme is tetrameric, has an ligand binding place close to the EKP conserved sequence and might prefer as substrate ketohexoses.
url http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/708
work_keys_str_mv AT mariusmihasan computerbasedmodelingforsugarpreferencesofanoxidoreducatsefromarthrobacternicotinovoranspao1plasmid
AT vladartenie computerbasedmodelingforsugarpreferencesofanoxidoreducatsefromarthrobacternicotinovoranspao1plasmid
_version_ 1724829926012485632