Computer-based modeling for sugar preferences of an oxidoreducatse from Arthrobacter nicotinovorans Pao1 plasmid
The pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an oxidoreductase from the megaplasmid was addressed. The experimental and modeling data...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
"Alexandru Ioan Cuza" University of Iași
2008-08-01
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| Series: | Analele Ştiinţifice Ale Universităţii Alexandru Ioan Cuza din Iași,Sectiunea II A : Genetica si Biologie Moleculara |
| Online Access: | http://www.gbm.bio.uaic.ro/index.php/gbm/article/view/708 |
| Summary: | The pAO1 megaplasmid of Arthrobacter nicotinovorans encodes two different pathways: one for nicotine
metabolism and an putative sugar catabolic pathway. Using computational methods, the preferences for sugar of an
oxidoreductase from the megaplasmid was addressed. The experimental and modeling data showed that the enzyme is
tetrameric, has an ligand binding place close to the EKP conserved sequence and might prefer as substrate ketohexoses. |
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| ISSN: | 1582-3571 2248-3276 |