Fertility Regulation in Male Rats by Implemented Tetraazamacrocyclic Compounds of Iron(II): Synthetic, Spectroscopic, and Applied Aspects With Toxicological Screening

<p>Antifertility and histopathological investigations were carried out on reproductive organs of male albino rats induced by tetraazamacrocyclic complexes of iron(II). The complexes were synthesized by the template condensation of 1,2-diaminoethane, 1,3-diaminopropane with succinic acid and ph...

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Bibliographic Details
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://www.hindawi.com/GetArticle.aspx?doi=10.1155/BCA/2006/17316
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Summary:<p>Antifertility and histopathological investigations were carried out on reproductive organs of male albino rats induced by tetraazamacrocyclic complexes of iron(II). The complexes were synthesized by the template condensation of 1,2-diaminoethane, 1,3-diaminopropane with succinic acid and phthalic acid in <mml:math> <mml:mrow> <mml:mn>2</mml:mn><mml:mo>:</mml:mo><mml:mn>2</mml:mn> </mml:mrow> </mml:math> molar ratios which are abbreviated as [<mml:math> <mml:mtext>Fe</mml:mtext> </mml:math>(<mml:math> <mml:msup> <mml:mtext>TAML</mml:mtext> <mml:mi>n</mml:mi> </mml:msup> </mml:math>)OAc] (<mml:math> <mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn>1</mml:mn> </mml:math> or 2 and <mml:math> <mml:msup> <mml:mtext>TAML</mml:mtext> <mml:mi>n</mml:mi> </mml:msup> </mml:math> represents tetraazamacrocyclic ligand). The complexes have been characterized by elemental analysis, conductivity measurements, IR, and electronic spectra.</p>
ISSN:1565-3633