Oleanolic acid ameliorates intestinal alterations associated with EAE

Oleanolic acid ameliorates intestinal alterations associated with EAE

Abstract Background Multiple sclerosis (MS) is a chronic demyelinating autoimmune disease affecting the CNS. Recent studies have indicated that intestinal alterations play key pathogenic roles in the development of autoimmune diseases, including MS. The triterpene oleanolic acid (OA), due to its ant...

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Bibliographic Details
Main Authors: Beatriz Gutierrez, Isabel Gallardo, Lorena Ruiz, Yolanda Alvarez, Victoria Cachofeiro, Abelardo Margolles, Marita Hernandez, Maria Luisa Nieto
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Neuroinflammation
Subjects:
Cytokines
EAE
Intestinal dysfunction
Inflammation
Immune markers
Mucins
Online Access:https://doi.org/10.1186/s12974-020-02042-6

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