Functional Analysis of the Aurora Kinase A Ile31 Allelic Variant in Human Prostate

Functional Analysis of the Aurora Kinase A Ile31 Allelic Variant in Human Prostate

Overexpression of the centrosome-associated serine/ threonine kinase Aurora Kinase A (AURKA) has been demonstrated in both advanced prostate cancer and high-grade prostatic intraepithelial neoplasia lesions. The single-nucleotide polymorphism T91A (Phe3lile) has been implicated in AURKA overexpress...

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Bibliographic Details
Main Authors: Noa Matarasso, Anat Bar-Shira, Uri Rozovski, Serena Rosner, Avi Orr-Urtreger
Format: Article
Language:English
Published: Elsevier 2007-09-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Aurora Kinase A
overexpression
cancer
prostate
NKTR
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800303

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