The local concentration of Ca2+ correlates with BMP7 expression and osseointegration in patients with total hip arthroplasty

The local concentration of Ca2+ correlates with BMP7 expression and osseointegration in patients with total hip arthroplasty

Abstract Background A successful osseointegration of total hip arthroplasty (THA) relies on the interplay of implant surface and bone marrow microenvironment. This study was undertaken to investigate the impact of perioperative biochemical molecules (Ca2+, Mg2+, Zn2+, VD, PTH) on the bone marrow ost...

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Bibliographic Details
Main Authors: Xiaodong Fu, Weili Wang, Xiaomiao Li, Yingjian Gao, Hao Li, Yi Shen
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Uncemented THA
Ca2+
BMP7
Stro-1+ cells
Osseointegration
Online Access:https://doi.org/10.1186/s13018-020-02090-x

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