Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

Human HLA-E can, in addition to self-antigens, also present pathogen-derived sequences, which elicit specific T-cell responses. T-cells recognize their antigen presented by HLA-E highly specifically and have unique functional and phenotypical properties. Pathogen specific HLA-E restricted CD8+ T-cel...

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Bibliographic Details
Main Authors:	Simone A. Joosten, Lucy C. Sullivan, Tom H. M. Ottenhoff
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Journal of Immunology Research
Online Access:	http://dx.doi.org/10.1155/2016/2695396

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