Activation of gene expression by detergent-like protein domains

Activation of gene expression by detergent-like protein domains

Summary: The mechanisms by which transcriptional activation domains (tADs) initiate eukaryotic gene expression have been an enigma for decades because most tADs lack specificity in sequence, structure, and interactions with targets. Machine learning analysis of data sets of tAD sequences generated i...

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Bibliographic Details
Main Authors: Bradley K. Broyles, Andrew T. Gutierrez, Theodore P. Maris, Daniel A. Coil, Thomas M. Wagner, Xiao Wang, Daisuke Kihara, Caleb A. Class, Alexandre M. Erkine
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:iScience
Subjects:
Biological sciences
Molecular biology
Bioinformatics
Computational bioinformatics
gene activation
transcriptional regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221009858

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http://www.sciencedirect.com/science/article/pii/S2589004221009858

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