Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current

Tetrodotoxin Sensitivity of the Vertebrate Cardiac Na+ Current

Evolutionary origin and physiological significance of the tetrodotoxin (TTX) resistance of the vertebrate cardiac Na+ current (INa) is still unresolved. To this end, TTX sensitivity of the cardiac INa was examined in cardiac myocytes of a cyclostome (lamprey), three teleost fishes (crucian carp, bur...

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Bibliographic Details
Main Authors: Jaakko Haverinen, Minna Hassinen, Matti Vornanen
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Marine Drugs
Subjects:
evolution of tetrodotoxin sensitivity
vertebrate animals
cardiac sodium current
Online Access:http://www.mdpi.com/1660-3397/9/11/2409/

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