Comparative Evaluation of Calcium-Sensitizing Agents, Pimobendan and SCH00013, on the Myocardial Function of Canine Pacing–Induced Model of Heart Failure

Pimobendan and SCH00013 are calcium sensitizers that possess dual action of calcium sensitization and phosphodiesterase-III inhibition. This study was conducted to comparatively evaluate the effect of these medications on the myocardial function of the canine pacing-induced heart failure model using...

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Bibliographic Details
Main Authors: Lina Hamabe, Keisuke Kawamura, Soo-min Kim, Rieko Yoshiyuki, Toshiharu Fukayama, Miki Shimizu, Ryuji Fukushima, Ryo Tanaka
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319301896

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