Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal.
FATP1 mediates skeletal muscle cell fatty acid import, yet its intracellular localization and metabolic control role are not completely defined. Here, we examine FATP1 localization and metabolic effects of its overexpression in mouse skeletal muscle. The FATP1 protein was detected in mitochondrial a...
Main Authors: | Maria Guitart, Oscar Osorio-Conles, Thais Pentinat, Judith Cebrià, Judit García-Villoria, David Sala, David Sebastián, Antonio Zorzano, Antonia Ribes, Josep C Jiménez-Chillarón, Celia García-Martínez, Anna M Gómez-Foix |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4032244?pdf=render |
Similar Items
-
Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells
by: David Sebastián, et al.
Published: (2009-09-01) -
Overexpressed FATP1, ACSVL4/FATP4 and ACSL1 increase the cellular fatty acid uptake of 3T3-L1 adipocytes but are localized on intracellular membranes.
by: Tianzuo Zhan, et al.
Published: (2012-01-01) -
Overexpression of CD36 and Acyl-CoA Synthetases FATP2, FATP4 and ACSL1 Increases Fatty Acid Uptake in Human Hepatoma Cells
by: Julia Krammer, Margarete Digel, Friedrich Ehehalt, Wolfgang Stremmel, Joachim Füllekrug, Robert Ehehalt
Published: (2011-01-01) -
Effect of Feeding Conditions on the Methylation Status of Fatp1 Gene in Chicken Breast Muscle
by: G Gao, et al. -
Hormonal regulation of long chain fatty uptake by adipocytes and studies of FATP gene family
by: Hirsch, David J
Published: (2010)