Vibrio fluvialis attachs to but does not enter Hela cell monolayers

• Main Authors: I. T. Carvalho, V. Magalhães, N. C. Leal, V. Melo, M. Magalhães
• Format: Article
• Language: English
• Published: Instituto Oswaldo Cruz, Ministério da Saúde 1994-06-01
• Series: Memórias do Instituto Oswaldo Cruz.
• Subjects: Vibrio fluvialis; Vibrio pathogenicity; diarrhea; HeLa cell adherence
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761994000200019

Considering the possibility that invasiveness could be a neglected factor of virulence in Vibrio fluvialis-linked enteritis, since a dysenteric form of the disease was seen in Bangladesh, we studied 12 Brazilian strains of the organism, six clinical and six environmental, to determine whether they might be able to enter into HeLa cell monolayers or would carry plasmids incidentally involved in invasiveness. Four human and two environmental isolates attached to but did not enter into the cells. Though five strains harbored plasmids,no relationship was found between the carriage of these genetic elements and adhesiveness.